For the three people in the world building the Rails mysql gem on a PowerPC G5-based OS X Server with the 64-bit MySQL installed getting this crazy error:

lazy symbol binding failed: Symbol not found: _mysql_init

The magic ninja gem install command that will cure all your ills goes a little something like this:

sudo env ARCHFLAGS="-arch ppc64" gem install -V mysql -- --with-mysql-include=/usr/local/mysql/include/ --with-mysql-lib=/usr/local/mysql/lib --with-mysql-config=/usr/local/mysql/bin/mysql_config --with-mysql-dir=/usr/local/mysql

Pretty obvious when you think about it. Not sure why it took me a little over an hour to discover the crucial lynchpin for correcting this system-wide thought-tastrophy.